Hepatitis C is a viral infection caused by the hepatitis C virus (HCV) that produces liver inflammation and damage. In 2014, a total of 2,194 cases of acute hepatitis C were reported to CDC from 40 states. An estimated 2.7-3.9 million people in the United States have chronic hepatitis C. According to the Health Resources and Services Administration (HRSA) Uniform Data System (UDS), in 2016, 695,822 patients were tested for Hep C in 1,367 Health Centers in the United States and its territories. An enormous public health danger lies in the fact that many infected patients are unaware of their condition. This webinar will review the ABCs of HCV infection as well as HCV drug therapy management in primary care.